Shimadzu Scientific Instruments (SSI) has released clinical laboratory automation module (CLAM-2030), a fully integrated sample pretreatment module for LCMS biological analysis. This innovation in automation improves laboratory efficiency, enables fast, precise results, and maintains low operating costs. By automating operations, such as dispensing, stirring, filtering, heating, and sample transfer, the system effectively improves data accuracy and achieves the reproducibility needed for clinical research and forensic toxicology. Such steps can be combined to perform tasks such as deproteination, internal standard addition, derivatization, and glucuronidase digestion.
The CLAM-2030 essentially facilitates the ability for users to reproducibly prepare samples and operate an LCMS regardless of their skill level. With a streamlined workflow that interfaces with LIS, users can easily create and run sample batches with minimal effort. STAT or emergency sample functionality allows users to prioritize urgent samples for quick results with minimal interruption. The system also offers a variety of functions that elevate research and business efficiency, as it automates processes including searching toxicological drug libraries, providing the optimal analytical method, facilitating data review, and generating reports. The module can measure hundreds of compounds in a single analysis, and makes it easy to change between different methods. Its flexible HPLC and MS configuration allows the unit to meet specific application needs. Through automation, the module helps to facilitate a safe working environment for laboratory personnel by minimizing human contact with potentially hazardous biological samples.