Innovation in diabetes and Hb-related disease diagnosis with Trivitron’s Nano H5 and Nano H110

High-performance liquid chromatography is a chromatographic technique that is performed to separate a mixture of compounds in analytical chemistry and biochemistry techniques, and it helps to identify and quantify the individual components of the target mixture present in the sample.

HPLC technology is the most advanced gold standard technology, and is being used globally for diagnosis and research. This technology offers full automation, complete walkaway, and high throughput, which are of prime importance for most clinical laboratories. The technique has become a routine tool in the separation of complex mixtures and is a method of choice as it offers high versatility and precision at a relatively low cost.

Hemoglobinopathies and diabetes are the most prevalent diseases that mostly affect the health of the majority of the Indian population. Diagnosis and monitoring of these diseases require advanced technologies, which can separate and quantitate complex molecules of hemoglobin (Hb) variants and glycated hemoglobin (HbA1c).

HPLC has become the recommended technology for thalassemia screening because of its speed and reliability. The technique is also widely used in the separation and quantification of glycated hemoglobin (HbA1c), which helps in the monitoring of diabetes.

Detection of structural hemoglobin (Hb) variants and thalassemia diagnosis has become increasingly important in clinical laboratories. Early detection of variants, such as HbS, has important therapeutic consequences and may lead to the appropriate application of preventive actions. Precise and accurate quantitation of these molecules is very important for diagnosis and treatment.

HbA1c is used for the diagnosis of diabetes, and it is now one of the most recommended tests by the International Committee and ADA for diabetes diagnosis and to detect retinopathy, nephropathy, and neuropathy.

Currently, HPLC technology is a widely accepted and proven technology, and globally it is used in various corporate hospitals, research centers, referral labs, and diagnostic centers.

Trivitron NANO H5 and NANO H110 are high-performance liquid chromatography analyzers for HbA1c and Thalassemia detection in less than 3 minutes. The working mechanism is based on ion-exchange chromatography and in ion exchange-HPLC, the separation is done based on the charge or ionic strength of the components in a sample mixture. These HPLC-based HbA1c analyzers are used for monitoring and management of diabetes, glycated hemoglobin, thalassemia, and hemoglobin variants. Both the analyzers are NGSP and IFCC recommended.

NANO H5 is a compact, automated HPLC analyzer that uses ion exchange liquid chromatography for the quantitative determination of glycated hemoglobin (HbA1c) in human whole blood with quick TAT by reporting results in less than 130 seconds. It has a large-screen display and inbuilt processor that is suitable for laboratories with small to medium workloads. The analyzer uses a whole-blood sample or diluted for the detection of the target molecule. The sleek design significantly takes less space on the bench.

The fully automated analyzer promises to process five samples at a time and has a unique barcode scanner for sample identification that will take Trivitron Healthcare to reach the pinnacle of precision within a designated time frame in the global diagnostic market.

NANO H110 is a compact, automated HPLC analyzer that has a dual-test mode for HbA1c test and Hb Variant detection. It has some advanced facilities, such as a barcode scanner and cap piercing, with a high sample loading capacity of 110 samples at a time, which makes it suitable for laboratories with medium to large workloads.

Early detection and diagnosis of diabetes and other blood genetic disorders can help to manage the condition at the initial phase. Modern diagnostic HPLC analyzers offered by Trivitron NANO H5 and NANO H110 can play an important role with proper disease diagnosis, monitoring and management that offers one with improved health after undergoing proper treatment at initial stages.