Suresh Kumar Chauhan
Managing Director,
Compact Diagnostics (India) Pvt. Ltd.

Compact Diagnostics India And Technoclone Gmbh: 10 Years Of Association

The promoters of Compact Diagnostics India Pvt Ltd have more than 25 years of experience in coagulation and installed the first fully auto coagulation analyzers in India in 1994. We are promoting Tecnoclone in India since 2009 and have more than 30 installations of fully auto and more than 500 installations of coagulometers.

Technoscreen ADMTS 13 Activity Kit is used for screening the deficiency of ADMTS 13 Activity in patients e.g. TTP (thrombotic thrombocytopenic purpura). It is a 30 minutes test that does not require any lab equipment or highly skilled personnel. For this test we use citrated plasma sample incubating it with vWF fragment where ADMTS 13 if present will cleave the fragment (20 minutes at RT). Detecting the presence/absence of cleaved fragment in flow through test device supplied in the kit using biotinylated detecting antibody and gold particles coupled with streptavidin (5 minutes).

Technoscreen ADMTS 13 Activity Kit is fast to determine the deficiency, simple, and easy to run the test with 100 percent positive predictive value defined for single patient. Reagent stability for one year after opening and it is for 10 samples. TTP patient with severe ADMTS 13 deficiency are more prone to relapse then patients without ADMTS 13 deficiency. Rapid diagnosis of TTP with ADMTS 13 has therapeutic advantages in sparing the use of PEX (plasma exchange) and plasma. Therapeutic uremic syndrome can be excluded by ADMTS 13. 

Pentade of TTP – Microangiopathic hemolytic anemia, thrombocytopenia, neurologic disturbances, renal failure, fever, etc.

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