Janssen to Highlight Data from Broad Rheumatology Portfolio at ACR Annual Meeting

The Janssen Pharmaceutical Companies of Johnson & Johnson announced that it will be presenting results from 20 abstracts across the company’s rheumatology portfolio and pipeline products during the 2018 American College of Rheumatology (ACR)/Association for Rheumatology Health Professionals (ARHP) Annual Meeting taking place in Chicago, IL, from October 19 – 24. New results from a Phase 2 trial evaluating STELARA (ustekinumab) in patients with active systemic lupus erythematosus (SLE) treated through one year will be presented in a plenary presentation on Tuesday, October 23, with additional data from that study also featured as an oral presentation. Data from a Phase 3 study of SIMPONI ARIA (golimumab) administered intravenously in patients with active psoriatic arthritis will also be featured in an oral presentation at the meeting.

These results highlight the depth and breadth of the Janssen rheumatology portfolio, advancing the understanding of the safety and efficacy of SIMPONI ARIA and STELARA, as well as TREMFYA (guselkumab) across multiple immune-mediated diseases, including moderately-to-severely active rheumatoid arthritis (RA), SLE, moderate-to-severe plaque psoriasis (PsO), active psoriatic arthritis (PsA) and active ankylosing spondylitis (AS). Beyond data from clinical programs, Janssen will also present findings from the real-world evidence AWARE trial (Comparative and Pragmatic Study of Golimumab IV Versus Infliximab in Rheumatoid Arthritis), which provides greater understanding of the use of SIMPONI ARIA in the standard clinical settings in RA. AWARE is an ongoing prospective Phase 4 comparator study designed to provide a real-world assessment of SIMPONI ARIA and REMICADE (infliximab) in patients with RA and part of Janssen’s growing focus on leveraging real world evidence to better understand treatment effectiveness in the clinical practice setting and the patient treatment experience.

“The broad range of data being presented at this year’s annual meeting spans the spectrum from clinical investigational studies to real world evidence about our marketed products like SIMPONI ARIA in clinical practice settings,” said Andrew Greenspan, M.D., Vice President, Medical Affairs Immunology, Janssen Scientific Affairs, LLC. “These studies build on our longstanding heritage of innovation in rheumatology and help further our understanding of potential new treatment pathways in diseases like lupus, where there is significant unmet patient need.” – Medical Buyer Bureau