Global CAR-T cell therapy market to reach USD 118,680.68 million by 2032

A latest research report with 360-Degree visibility, titled “CAR-T cell therapy market share, size, trends, industry analysis report, by target antigen (CD19/CD22, BCMA, and others); By indication; By region; segment forecast, 2023 – 2032” published by Polaris Market Research in its research repository.

“According to research report, the global car-t cell therapy market size/share was valued at USD 3,010.24 Million in 2022 and is expected to touch USD 118,680.68 Million By 2032, growing at a CAGR of 43.2% during the forecast period.”

Report overview
CAR-T cell therapy, known as Chimeric antigen receptor, is a ground-breaking new component in cancer treatment. It treats specific cancers by turning your T-cells into more effective cancer-fighting machines. This treatment has shown considerable promise in curing some types of blood cancers by using your own immune cells to combat cancer, resulting in increased demand for the CAR-T cell therapy market.

With CAR-T cell treatment, immune cells named T cells are taken out of the blood and given a new gene that makes them capable of identifying cancer. The T cells are injected back into the circulation once the gene has been added, where they multiply and start a range of immunological reactions meant to kill the cancer cells. It treats particular types of cancer like pediatric leukemia, lymphoma, and adult leukemia.

Some of the top market players are:

• Amgen Inc. (US)
• Bellicum Pharmaceuticals Inc. (US)
• Bluebird Bio (US)
• Caribou Biosciences Inc. (US)
• Celgene Corporation
• Cellectis
• Celyad
• Gilead Sciences Inc.
• Intellia Therapeutics
• Johnson & Johnson
• Merck KGaA
• Nanjing Legend Biotechnology Co. Ltd.
• Noile-Immune Biotech
• Novartis International AG
• Pfizer Inc.
• Sangamo Therapeutics Inc.
• Servier Laboratories

Key growth driving factors

• Increased Prevalence of Cancer: During the projection period, the number of patient assistance programs, government initiatives to raise cancer awareness, and growing cancer prevalence all contributed to the CAR-T cell therapy market growth.
• Identification of CAR-T Therapy Potential: The potential of CAR-T cell therapy has been acknowledged by biotechnology companies, major pharmaceutical businesses, and academic associations, who have invested greatly in this field. These investments seek to increase manufacturing capacity, accelerate R&D, and increase access to CAR-T therapy for more patients.
• Increased Investments: The market has made great progress due to increased investment, with various medicines getting regulatory authorization and going on sale. The additional funding is anticipated to accelerate CAR-T therapy development and commercialization, opening the door for more effective and individualized cancer treatments.

Segmental analysis

• CD19/CD22 holds the greatest market share

CD19/CD22 dominates the Car-T cell therapy market share. Impressive clinical results have been seen with CD19-targeted CAR-T therapy when treating specific forms of lymphoma and leukemia. They have received regulatory approval and have proven effective in causing patient remission.

The market dynamics are evolving, and the development of BCMA-targeted CAR-T treatments for multiple myeloma has attracted much interest. Myeloma cells strongly express BCMA, which makes it a desirable target for CAR-T cell treatment. BCMA-targeted CAR-T treatments have demonstrated excellent response rates and long-lasting remissions in patients with relapsed or refractory multiple myeloma in early clinical trials, which have yielded encouraging findings.

• Diffuse Large B-Cell Lymphoma (DLBCL) holds the largest share

DLBCL is one of the most prevalent types of non-Hodgkin lymphoma and is characterized by rapidly growing tumors of B-cell origin. It is a significant indication in the CAR-T cell therapy market and holds a considerable market share.

The use of CAR-T cell therapy in treating DLBCL has delivered encouraging results. CAR-T therapy improves the immune system’s capacity to identify and destroy cancer cells by genetically altering a patient’s own T cells to express CARs that target particular proteins in cancer cells.

Geographical overview

• North America: A growing number of cancer patients and the development of the biotech industry in North America are likely to make the region the leader in the worldwide CAR-T cell treatment industry. The number of cancer cases in North America is rising, driving demand for cancer treatments there.
• European Countries: The CAR-T treatment market will expand quickly due to changing European market trends and the rising adoption of suitable technology. The Committee for Medicinal Products for Human Use (CHMP) gave Kymriah and Yescarta favorable reviews, making them the first medications funded by the EMA’s Priority Medicines (PRIME) program. As a result, an increase in CAR-T cell therapy market size is anticipated.

Recent developments

• Seattle Genetics, Inc. and Merck teamed together in September 2020 for two strategic oncology trials to create cures for various malignancies. Individuals with melanoma with lymph node involvement following surgery will receive Merck’s KEYTRUDA as adjuvant therapy as part of the agreement.
• Atara Biotherapeutics, Inc. and Bayer AG partnered in December 2020 to create mesothelin-targeted CAR T-cell treatments for solid tumors. By progressing ATA2271 for treating malignant pleural mesothelioma and non-small-cell lung cancer, this partnership established Atara as a top producer of allogeneic CAR-T cell therapy.

Polaris Market Research