Infusion Pumps
Infusion pumps – The epitome of precision and programmable care
Infusion pumps have come a long way, transitioning from their mechanical roots to become the epitome of precision and programmable care that they are today.
Infusion pumps have become a ubiquitous presence in healthcare settings, playing a fundamental role in the precise and controlled delivery of medications, fluids, and nutrients to patients. They deliver fluids including nutrients and medications, such as insulin, chemotherapy drugs, antibiotics, pain relievers, and hormones into a patient’s body in a controlled manner.
Pivotal in ensuring patients receive the right treatment in a carefully regulated manner, they have undergone a profound transformation from their early mechanical origins. Today’s infusion pumps are sophisticated, digitally interconnected systems, distinguished by their precision, programmability, and advanced safety features.
Indian market
The Indian infusion pumps market in 2023 is estimated as ₹5450 crore, poised to reach ₹8250 crore in 2029, with a CAGR of 7.18 percent during 2023 to 2029.
Major players include AKAS Infusions, BD, Baxter International Inc., Medtronic plc., Fresenius Kabi AG, Terumo Corporation, Roche Diagnostics India Pvt. Ltd., Johnson & Johnson Private Limited, Braun Melsungen AG, Smiths Medical India Pvt. Ltd., Nipro India Corporation Pvt. Ltd., Zynova Pharmaceuticals Pvt. Ltd., Nikkiso Co., Mindray Medical India Pvt. Ltd., Stryker Corporation, Skanray, and Allied Medical. The manufacturers are constantly improving their forward integration capabilities in the value chain and establishing and enhancing distributor network.
Moreover, since the infusion pumps market is highly fragmented, there is no definite leader for all categories, leaving enough scope for investment by mushrooming local players. Players dealing with hospital supplies are increasingly targeting the infusion pumps market for either acquiring leading companies or those facing large number of product recalls.
Diabetes segment holds the largest share in the India infusion pumps market owing to the high prevalence of this chronic condition among Indians. The National Center for Biotechnology Information, in India, estimates that from 77 million people having diabetes in 2019, by 2045, the number is projected to reach over 134 million, which is directly influencing the demand for infusion pumps in India. Other applications include oncology, diabetes, gastroenterology, analgesia/pain management, hematology, pediatrics, and neonatology.
The market is split into stationary and ambulatory segments. The stationary infusion pumps segment accounts for a higher market share. Stationary IV pumps are frequently used to give intravenous fluid resuscitation to more than 30 percent of ICU patients. Complex pharmaceutical regimens, including chemotherapy or cardiac anesthetics, can be administered with these pumps. However, the ambulatory IV pumps are projected to register a higher CAGR owing to the inconvenience caused by their stationary counterparts during their transportation.
The market, segregated into large-volume infusion pumps, syringe infusion pumps, insulin pumps, enteral feeding pumps, elastomeric pumps, and implantable pumps, reports that, owing to the high prevalence of type 1 diabetes in the country, the insulin pumps hold the highest share in the Indian infusion pump market. Compared to traditional insulin injection therapy, insulin pumps have a variety of benefits, including a more accurate dosage and the capacity to continuously monitor blood glucose levels.
Development of smart pumps and wireless connectivity and government initiatives to provide affordable and accessible healthcare are some major factors expected to boost the growth of the market. However, high cost of infusion pumps typically between ₹20,000 and ₹150,000 make it expensive for some people and even if advised by their doctor, they are not able to afford insulin pump therapy.
Infusion pump technology
Amrith Rangan
CEO,
AKAS Medical Equipment
Infusion pumps are vital medical devices used to administer a wide range of fluids, including medication and nutrients directly into a patient’s circulatory system in a continuous and controlled manner. This article explores the information regarding infusion pumps and highlighting the new technology of infusion pumps in the healthcare industry.
There are different types of infusion pumps, such as volumetric infusion pumps, syringe pumps, PCA pump, etc. The PCA pump allows the patient to self-administer pain relief within a preset dosage limit; insulin pump is especially designed for diabetes patients to deliver a continuous supply of insulin to manage their blood sugar level; ambulatory and wearable infusion pump allows the patient to get treatment in high degree of mobility, thereby reducing the need for extended hospital stays.
The technology advances in infusion pumps have transformed the treatment of patients in hospitals as well as afforded the ability to receive treatment while going about their daily lives. These pumps ensure that patients receive the best care.
Advanced technology of infusion pumps and the integration of wireless connectivity help healthcare providers to remotely monitor and control the infusion rates, receiving real-time data on patient vitals. Most of the smart pumps come up with AI technology to reduce medication errors and enhancing the treatment effectiveness.
Advances in genetics and personalized medicine are leading to the development of infusion pumps that can deliver treatments tailored to a patient’s genetic makeup. This approach promises more effective and individualized care, particularly in oncology and chronic disease management.
Another technology of infusion pumps is implantable infusion pump, typically considered when the patient requires continuous, targeted therapy and who requires long-term treatment.
Nowadays, infusion pumps come equipped with so many safety features and alarm systems to detect and prevent the potential issues, enhancing patient safety. Many also have drug libraries to prevent medication errors.
Their diverse range of types and applications, coupled with evolving technology, continue to enhance patient care, reduce medication errors, and improve the overall quality of medical treatment. As medical science advances, so too will the capabilities of infusion pumps, contributing to the ongoing evolution of healthcare.
Global market
The global infusion pumps market, valued at USD 13 billion in 2022, is expected to reach USD 27 billion by 2033, at a CAGR of 8 percent. The infusion pumps market has broadened its horizon, primarily due to increase in chronic kidney diseases and stomach-related diseases. Moreover, mounting spending on medicine R&D and significantly emerging demand for infusion pumps in home care facilities are expected to provide the requisite impetus.
Furthermore, the increase in the number of surgical procedures performed across the globe, growing cases of medication errors, and high demand for ambulatory infusion pumps are other factors that are anticipated to boost the growth of the global infusion pump market.
Skyrocketing demand for infusion pumps in neonatology as the WHO estimated that nearly 6700 newborn babies die each day summing up to 47 percent of death of children aged under 5 years across the globe is developing the demand for infusion pumps.
In terms of forward strategy, companies are manufacturing user-friendly and technologically advanced infusion pumps that can be monitored remotely. Companies are also including comprehensive drug libraries in pumps that would enable multi-directional interoperability and enhanced data safety of the instrument and patients, for better electronic health record and medication management across multi-care settings. Lastly, advanced technologies, including dose error reduction system (DERS) and barcode-enabled point of care (BPOC) systems, are also being incorporated in infusion pumps to prevent medication errors, thereby, driving growth.
However, a booming number of medication errors, lack of requisite technology like wireless connectivity, and requirement of higher initial investment are some significant constraints hindering the expansion of the market.
Regional insights. North America accounts for 43 percent of the market. The reasons are many, the most important being technologically advanced medical infrastructure which relies on infusion pumps to accurately administer medications and fluids. Rise in the number of aged patients with diseases, such as diabetes, cardiovascular disease, and cancer is the reason for the region holding the largest chunk of the market share.
Asia-Pacific is projected to observe significant amount of growth and the fastest growing region in the Asia-Pacific infusion pumps market due to the rise in the occurrence of outsourcing organizations. Moreover, the increasing healthcare expenses is further anticipated to propel growth in the region in the coming years.
Pioneering medical devices innovations – A glimpse
Infusion systems represent a synergy between cutting-edge technology and advanced safety features. They provide real-time monitoring and data-driven support, enabling healthcare providers to maintain precision and accuracy in treatment. One of their key attributes is dose calculation support, which significantly reduces the potential for incorrect dosages. By offering alerts and alarms, these systems act as an additional layer of safety, ensuring that medical professionals are promptly informed of any deviations from the treatment plan.
The essence of these systems lies in their proactive approach to patient care. They are designed to minimize the risk of errors by providing comprehensive safety checks, including drug interaction alerts and dose limits. By constantly monitoring the infusion process and ensuring adherence to treatment parameters, these systems contribute to error reduction, improving patient outcomes and well-being.
The interlinked themes of safety and error reduction are ingrained in the design and functionality of these infusion systems. They serve as a safeguard against the potential risks associated with infusion therapy, making them an essential component of modern healthcare. As the industry continues to innovate, the future of patient care promises to be marked by enhanced safety, precision, and error reduction, ensuring that patient well-being remains at the forefront of healthcare delivery.
Next-generation infusion pumps are poised to revolutionize the way healthcare is delivered. These advanced devices offer a range of features that not only enhance precision but also streamline the treatment process. The transformation of infusion pumps into smart devices, indicating their integration with modern technologies, including connectivity and data-driven capabilities. As the healthcare sector embraces digitization, these smart pumps play a pivotal role in improving the efficiency and effectiveness of patient care. Their ability to provide real-time data and connectivity with electronic health records contributes to the seamless delivery of treatment and the potential for proactive adjustments.
Their potential to reduce medication errors and enhance patient safety is evident, as they serve as a valuable tool in the hands of healthcare professionals, ensuring precise delivery of medications and fluids.
Moreover, the interconnected nature of next-generation infusion pumps extends beyond their immediate applications. These pumps empower patients to be partners in their care, promoting a sense of control and collaboration in their treatment plans. The transformative potential of these technologies aligns with the evolving dynamics of patient-centered care.
The impact of next-generation infusion pump technology transcends individual devices. It extends to the broader healthcare system and its efficiency. The integration of data-driven capabilities in next-generation pumps allows for comprehensive monitoring, analysis, and reporting. This data-driven approach aids healthcare providers in making informed decisions, optimizing resource allocation, and predicting patient needs. As a result, healthcare systems become more adaptive and responsive, ultimately leading to better patient outcomes.
Next-generation infusion pump technology represents a significant milestone in the journey toward enhanced patient care.
The realm of IoT (Internet of Things) programmable infusion pumps represents a significant leap in the infusion pump industry, creating a bridge between technology and patient care.
These devices leverage IoT technology to provide real-time monitoring and control of drug delivery, improving the accuracy and efficiency of the delivery process. They offer a range of functionalities, including data collection, and remote adjustments. This interconnectedness introduces a new era of treatment, where healthcare providers can deliver care with enhanced accuracy and adaptability. These devices are instrumental in reducing errors, increasing patient safety, and optimizing treatment regimens.
Revolutionizing medication delivery – The advanced world of infusion pumps
Aditya Kohli
CFO & Director,
Allied Medical Limited
In the realm of modern healthcare, infusion pumps play a pivotal role in precisely delivering medications and fluids to patients. These devices have evolved significantly, incorporating cutting-edge technologies, such as touch screens to enhance functionality and user experience. The integration of touch screens in infusion pumps has streamlined their operation, offering an intuitive and user-friendly interface. Healthcare professionals can easily navigate through settings, adjust dosages, and monitor infusion progress with a simple touch. This not only reduces the risk of human error but also enhances the overall efficiency of medication administration. Infusion pumps typically come with standard modes, ensuring basic functionality. These include continuous mode for a steady flow of medication and bolus mode for rapid administration. These modes provide healthcare providers with flexibility in tailoring treatment plans to individual patient needs. In the contemporary landscape of technological progress, infusion pumps incorporate advanced operational modes that significantly enhance their capabilities. The ramping mode, for instance, facilitates a gradual adjustment of medication dosage, thereby minimizing the risk of adverse reactions and enhancing patient tolerance. The dosage mode provides healthcare professionals with a tool for precise control over the administered medication, ensuring accuracy and customization in treatment. Additionally, the sequence mode permits the sequential delivery of various medications or fluids, presenting a versatile solution for managing complex treatment regimens. Furthermore, the implementation of relay modes streamlines the transition between multiple pumps, guaranteeing a continuous and uninterrupted flow of medication.
Innovations in infusion pump technology extend beyond the pumps themselves to include advanced docking stations. These stations are designed to accommodate multiple pumps simultaneously, providing a centralized and organized solution for medical professionals. The ability to power multiple pumps through a single cord reduces clutter and simplifies the setup process.
The integration of touchscreens and advanced operational modes, coupled with the convenience of advanced docking stations, represents a significant leap forward in medication delivery. These advancements contribute to safer, more efficient, and patient-centric healthcare practices, ultimately improving the quality of care in modern medical settings.
Implantable sensor-based pumps deliver drugs, such as pain medications or chemotherapy, directly to the site of action. The pumps can be controlled wirelessly using a smartphone or other devices, allowing healthcare providers to adjust the delivery rate as needed.
However, these very advancements expose insulin pumps to potential cyber threats. The interconnected nature of healthcare systems means that insulin pumps are not isolated; they are part of an intricate network susceptible to unauthorized access.
The FDA and OEMs have worked together to make security-by-design a priority for the growing medical devices industry. However, hospitals operate within a complex ecosystem of data, devices, and stakeholders. Legacy devices that were not intended for connectivity operate alongside mobile devices designed for IoT; third-party TCP/IP stacks, and other tools cannot always account for these discrepancies. Older operating platforms, such as early versions of Windows, remain vulnerable to old malware.
Driving growth in the home infusion therapy market
The home infusion therapy market is currently experiencing substantial growth, with the infusion pumps segment playing a pivotal role in this expansion.
This shift is driven by several factors, including the rising prevalence of chronic conditions, the aging population, and the growing emphasis on cost-effective and patient-centric healthcare.
These pumps are designed to be user-friendly and easy to operate, making them well suited for home-based care. Their ability to provide accurate dosing and safety features ensure that patients receive the right treatment under the guidance of healthcare professionals. Moreover, the ongoing advancements in infusion pump technology further contribute to the expansion of home infusion therapy market.
Wearable infusion pumps that deliver medication through a catheter under the skin are also gaining popularity. They are portable, discreet, and programmed to administer precise doses at specific times, providing continuous medication throughout the day. Wearable infusion pumps offer convenient and mobile delivery of medication while minimizing infection risk by avoiding disturbance to the infusion site. They offer precise dosing and can adjust medication based on real-time glucose levels for personalized treatment.
Evaluating insulin therapy – Research discoveries
The National Center for Biotechnology Information (NCBI) explores the use of ultra-rapid versus rapid-acting insulin in infusion pumps. This study delves into a critical aspect of diabetes management, examining the efficacy and safety of different insulin delivery methods. Ultra-rapid insulin showed better performance in maintaining blood glucose within the target range and reducing time spent in hypoglycemia compared to rapid-acting insulin. There was no significant difference in hyperglycemia between the two insulin types. Additionally, the ultra-rapid insulin resulted in a significant decrease in post-meal blood sugar levels. However, the study found that the use of ultra-rapid insulin was associated with a higher likelihood of unexpected changes in the infusion set, particularly when used in sensor-augmented pump systems.
Enhancing cyber-security in insulin pump technology
A recent study has shed light on cyber-security vulnerabilities in infusion pumps. The study reveals that three out of four infusion pumps are susceptible to cyber-attacks, underscoring the growing importance of digital security in healthcare. As infusion pumps transition into digitally interconnected systems, they become more efficient and customizable. However, this transformation also necessitates stringent cyber-security measures. This update serves as a wake-up call for the industry, prompting it to prioritize
not only technological advancements but also robust safeguards against potential threats.
As the convergence of data science and medical devices cyber-security becomes pivotal in ensuring the safety of patients and the effectiveness of healthcare, the focus now extends to insulin pumps.
In this context, data science plays a vital role. It is a potent tool in detecting potential cyber-security threats to insulin pumps. By analyzing data generated by these devices, data scientists can identify patterns or anomalies that indicate unauthorized access or tampering. Predictive analytics, powered by data science, can also help in anticipating and preventing potential risks, ensuring a proactive approach to security.
The secure disposal of these devices is another significant concern. Improper de-acquisition can leave residual patient data accessible, risking privacy and data security. Healthcare providers must establish stringent protocols for secure device disposal and data sanitization.
The infusion pump industry stands at the forefront of healthcare innovation, continually advancing to ensure better patient care and safety. From regulatory compliance and cyber-security in connected devices to ground-breaking developments in insulin therapy, the industry is unwavering in its commitment to improving treatment precision and patient outcomes. This progress extends globally, addressing the specific healthcare needs of regions like India, while propelling the home infusion therapy market forward. Next-generation infusion pumps, IoT integration, and data-driven analytics are transforming healthcare delivery. Still, it is essential to recognize the critical role data science plays in enhancing cyber-security, ensuring the utmost safety for patients reliant on insulin pumps. Together, these advancements exemplify the industry’s dedication to patient-centered, technologically driven care.
